The Mystery Behind Histamine Intolerance

Are you reacting from food but can’t pinpoint what food you are reacting from? Do you have multiple unexplained symptoms? Have you had testing from different specialist such as cardiologist, allergist, and gastroenterologist but testing came back normal? It’s possible you may have a histamine intolerance.

Histamines are compounds found in mast cells that are involved in our innate (immediate) and adaptive (acquired) immune system. There are people who have a variant of the Diamine Oxidase (DAO) enzyme and are unable to break down histamines in the body. Histamine intolerance occurs when histamine builds up in the body from eating foods high in histamines or foods that increase histamines, which can develop a multitude of symptoms.

Symptoms of Histamine Intolerance include:

Headaches or migraines

Vertigo or dizziness


Nasal congestion, sneezing, difficulty breathing


Swelling of face/lips/tongue (angioedema), hands, and feet 



Arrhythmia, or accelerated heart rate

Nausea, vomiting

Abdominal cramps

Difficulty falling asleep

Difficulty regulating body temperature


Abnormal menstrual cycle

If you have multiple symptoms, follow up with a Functional Medicine Practitioner to determine if you have a histamine intolerance and the root causes.

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