Immune Supplements for COVID19

The coronavirus has been found to release pro-inflammatory cytokines. Cytokines are messengers of the immune system that send signals to cells to increase inflammation in the body. When too many are released, this is called cytokine storm. Some people with the COVID19 have developed this cytokine storm which leads to severe complications and sometimes death. So how can this be prevented?

Many studies have shown with other coronaviruses (SARS-COV), the mechanism of action is stimulating NLRP3 inflammasome which causes the release of the pro-inflammatory cytokines IL-1 beta. Studies have shown natural botanicals and nutrients have the ability to prevent activation of the NLRP3 inflammasome. There is no cure for the coronavirus, but the goal should be to lower inflammation in the body and support the immune system so if someone does get exposed, they have an immune system strong enough to fight and keep inflammation down to improve outcomes and reduce complications.

Recommended coronavirus immune support if symptomatic:

  • Vitamin D 5000-10000 IU daily – supports immune system defense, reduces cytokines
  • Vitamin C 1000-3000mg daily – immune system support
  • Omega 3 1000-2000mg total EPA/DHA – inhibits NLRP3
  • Zinc 30-100mg daily – inhibits replication and attachment of virus, immune system support
  • Quercetin 1000mg twice daily – inhibits NLRP3, zinc isophore, anti histamine, inhibits viral replication
  • Curcumin 500-1000mg twice daily – inhibits NLRP3
  • Resveratrol 100-150mg daily – inhibits NLRP3
  • N-acetyl cysteine (NAC) 600-900mg twice daily – inhibits viral replication, lowers oxidative stress, 
  • Curcumin 500mg-1000mg twice daily – inhibits NLRP3
  • Elderberry – use as directed (avoid with autoimmune disorders)
  • EGCG (Epigallocatechin found in green tea) 4 cups daily -modulates NLRP3 and is a zinc isophore

Resources:
IFM – The Functional Medicine Approach to COVID-19: Virus-Specific Nutraceutical and Botanical Agents

https://www.hindawi.com/journals/mi/2016/5460302/

https://www.ncbi.nlm.nih.gov/pubmed/19732754

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834330/

https://www.ncbi.nlm.nih.gov/pubmed/18751910 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834330/

Disclaimer: These are recommendations and not meant for treatment, substitute for medical advice, nor are they FDA approved. Before taking any supplement, follow up with a medical practitioner to determine which supplements can be taken.